SubtiBank SubtiBank
yfmG [2017-8-11 16:0:3]
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yfmG [2017-8-11 16:0:3]

unknown
locus
BSU07480
pI
5.18
mw
56.37 kDa
protein length
487 aa Sequence Blast
gene length
1461 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]
  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

    • Gene

    Coordinates
    820,867 → 822,330

    The protein

    Modification

  • phosphorylated on Arg-474 [Pubmed|22517742]

    • Expression and Regulation

    Operons

    genes
    [gene|8A9E5A121CA2C5CE8A7A2DD2FDCE2AD5FCB356BF|yfmH]-[gene|893BB8D1B43F10B46BB7F2DBFE9BE63E9AEEE8EB|yfmG]
    description
    [Pubmed|32611709]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [pubmed|32611709], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]
  • [protein|8A9E5A121CA2C5CE8A7A2DD2FDCE2AD5FCB356BF|YfmH]: attenuation, [pubmed|32611709], in [regulon|8A9E5A121CA2C5CE8A7A2DD2FDCE2AD5FCB356BF|YfmH regulon]

    • regulation

  • repressed by glucose (4-fold) [Pubmed|12850135]

    • additional information

  • A [protein|search|ncRNA] is predicted between [gene|3DFC1A118B346C7939851BF711FFA31E04A698E8|yfmI] and [gene|893BB8D1B43F10B46BB7F2DBFE9BE63E9AEEE8EB|yfmG], this has been shown to encode the leader peptide, [protein|8A9E5A121CA2C5CE8A7A2DD2FDCE2AD5FCB356BF|YfmH] [PubMed|32611709,20525796]
  • Expression of [gene|893BB8D1B43F10B46BB7F2DBFE9BE63E9AEEE8EB|yfmG] is controlled by [protein|8A9E5A121CA2C5CE8A7A2DD2FDCE2AD5FCB356BF|YfmH]-mediated attenuation: slow translation rates of [protein|8A9E5A121CA2C5CE8A7A2DD2FDCE2AD5FCB356BF|YfmH] due to amino acid limitation prevent the formation in the [gene|893BB8D1B43F10B46BB7F2DBFE9BE63E9AEEE8EB|yfmG] leader (reduced expression of [gene|893BB8D1B43F10B46BB7F2DBFE9BE63E9AEEE8EB|yfmG] if amino acids are available in excess) [pubmed|32611709]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-C243 (yfmG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2241 NBRP B. subtilis, Japan]

    • References

  • 22517742,20817675,21815947,12850135,20525796